Author

Cui Chen

Chinese Academy of SciencesORCID 0000-0002-6053-3971Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Research Focus:perturbation response prediction· 1 Research Focus:sequence-to-function modeling· 1

Frequent Co-Authors

Chunhui WuiD· 1 shared Feipu YangiD· 1 shared Feisheng ZhongiD· 1 shared He YangiD· 1 shared Hualiang JiangiD· 1 shared Jingshan SheniD· 1 shared Mingyue ZhengiD· 1 shared Qingjie ZhaoiD· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBioinformatics

Chunhui WuORCID

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1 paper

Recent·Most cited

Automated design and optimization of multitarget schizophrenia drug candidates by deep learning

Xiaoqin Tan, Xiangrui Jiang, He Yang, Feisheng Zhong, Xutong Li, Zhaoping Xiong, Zhaojun Li, Xiaohong Liu, Cui Chen, Qingjie Zhao, Yuanchao Xie, Feipu Yang, Chunhui Wu, Jingshan Shen, Mingyue Zheng, , Hualiang Jiang

This paper develops a deep learning system to design multitarget antipsychotic drugs, generating novel compounds with activity against multiple receptors and demonstrating efficacy in animal models.

European Journal of Medicinal Chemistry · Jul 11, 2020Peer-reviewedBioinformatics