Author

Anuli Christiana Uzozie

University of British ColumbiaORCID 0000-0003-2000-2532Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genetic & Genomic Medicine· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Philipp F. LangeiD· 3 shared Antoine H. C. van KampeniD· 1 shared Clara van KarnebeekiD· 1 shared David T S LiniD· 1 shared Emma GrahamiD· 1 shared Filip Van PetegemiD· 1 shared Frans M. van der KloetiD· 1 shared Frédéric Maxime VaziD· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersMolecular Biology

Philipp F. LangeORCID

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3 papers

Recent·Most cited

A TBP-independent mechanism for RNA Polymerase II transcription

James Z.J. Kwan, Thomas F. Nguyen, Anuli Christiana Uzozie, Marek A. Budzyński, Jieying H Cui, Joseph MC Lee, Filip Van Petegem, Philipp F. Lange, Sheila S. Teves

The paper shows that TBP is not essential for Pol II transcription in mESCs, revealing a TBP-independent mechanism for transcription initiation.

eLife · Mar 30, 2023Peer-reviewedMolecular Biology

Sensitive identification of known and unknown protease activities by unsupervised linear motif deconvolution

Anuli Christiana Uzozie, Theodore G. Smith, Siyuan Chen, Philipp F. Lange

The paper introduces RoLiM, an algorithm for detecting protease activities in peptide data, identifying known and novel cleavage patterns in cancer and viral contexts.

Analytical Chemistry · Jan 14, 2022Peer-reviewedBioinformatics

Multi-omic approach to identify phenotypic modifiers underlying cerebral demyelination in X-linked adrenoleukodystrophy

Phillip A. Richmond, Frans M. van der Kloet, Frédéric Maxime Vaz, David T S Lin, Anuli Christiana Uzozie, Emma Graham, Michael Steffen Kobor, Sara Mostafavi, Perry D. Moerland, Philipp F. Lange, Antoine H. C. van Kampen, Wyeth W. Wasserman, Marc Engelen, Stephan Kemp, Clara van Karnebeek

This study uses multi-omic profiling of blood samples from ALD patients to identify molecular markers predictive of cerebral demyelination, but finds no statistically significant markers due to high inter-individual variation.

Frontiers in Cell and Developmental Biology · Jun 25, 2020Peer-reviewedGenetic & Genomic Medicine