Unraveling the therapeutic mechanism of deep-brain stimulation
Bastijn J.G. van den Boom, Alfredo Elhazaz Fernandez, Peter A. Rasmussen, Enny H. van Beest, Aishwarya Parthasarathy, Damiaan A J P Denys, Ingo Willuhn
This study investigates how deep-brain stimulation (DBS) affects neuronal activity and behavior in a mouse model of compulsive grooming, finding dose-dependent effects and specific involvement of the medial orbitofrontal cortex.
bioRxiv · Dec 23, 2022 · PreprintNeuroscience