Aishwarya Parthasarathy

This study investigates how deep-brain stimulation (DBS) affects neuronal activity and behavior in a mouse model of compulsive grooming, finding dose-dependent effects and specific involvement of the medial orbitofrontal cortex.

The paper identifies two independent low-dimensional subspaces in the lateral prefrontal cortex for working memory and motor preparation, showing how they maintain information separation despite shared neuronal populations.

The paper shows that dynamic prefrontal activity contains stable memory information, which depends on parallel movement of memory-related trajectories in state space.