Hedgehog-Hippo pathway interactions promote T cell exclusion from the tumor microenvironment in basal cell carcinoma
Georg Stockmaier, Suraj R. Varkhande, Peter William Krenn…·Fritz Aberger
This study shows that HH/GLI and Hippo/YAP pathway interactions suppress T cell chemotaxis and promote immunosuppression in BCC by downregulating chemokine signaling.