H Auguste Dutcher

The paper identifies RBPs interacting with Ssd1 in yeast aneuploidy tolerance through network analysis and genetic experiments, revealing roles in translational repression and p-body formation.

The paper investigates the response to single-gene duplication in yeast, finding that translation-related genes are particularly deleterious in aneuploid cells lacking the RNA-binding protein Ssd1.

The paper quantifies the fitness cost of aneuploidy in yeast by analyzing chromosome duplications and identifies gene length as a key determinant of toxicity.