Author

Julie Rojas

University of Wisconsin–MadisonORCID 0000-0001-8714-1532Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Genomics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Organism:yeast· 2 Research Focus:benchmarking· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Audrey P. GaschiD· 3 shared H Auguste DutcheriD· 2 shared James Hose· 2 shared Andrea GalmozziiD· 1 shared Andrew J. SmithiD· 1 shared Anna Pashkova· 1 shared Caroline FecheriD· 1 shared Chris Todd HittingeriD· 1 shared

Activity by Year

2024-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersGenetics

Audrey P. GaschORCID

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3 papers

Recent·Most cited

GeneticsPLoS GeneticsPeer-reviewedOct 25, 2024

The response to single-gene duplication implicates translation as a key vulnerability in aneuploid yeast

H Auguste Dutcher, James Hose, Hollis Howe…·Audrey P. Gasch

The paper investigates the response to single-gene duplication in yeast, finding that translation-related genes are particularly deleterious in aneuploid cells lacking the RNA-binding protein Ssd1.

11 citations

yeaststatistical model

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GenomicsCell GenomicsPeer-reviewedSep 23, 2024

Comparative modeling reveals the molecular determinants of aneuploidy fitness cost in a wild yeast model

Julie Rojas, James Hose, H Auguste Dutcher…·Audrey P. Gasch

The paper quantifies the fitness cost of aneuploidy in yeast by analyzing chromosome duplications and identifies gene length as a key determinant of toxicity.

22 citationstop 3%

yeastDNA methylation

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Systems BiologyNature CommunicationsPeer-reviewedAug 15, 2024

Fast and Deep Phosphoproteome Analysis with the Orbitrap Astral Mass Spectrometer

Noah M. Lancaster, Pavel G. Sinitcyn, Patrick Forny…·Joshua J. Coon

The paper introduces a method using the Orbitrap Astral mass spectrometer with DIA to rapidly analyze phosphoproteomes, detecting over 80,000 phosphorylation sites in mice.

83 citationstop 1%

humanmouse

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