Philippe Horvath

This study identifies novel antiviral defense systems in Streptococcus thermophilus by analyzing genomic islands, revealing previously uncharacterized systems and highlighting their role as reservoirs of bacterial immunity.

This study identifies and validates 21 accessory defense systems in S. thermophilus, showing that some provide stronger phage resistance than CRISPR-Cas, especially when combined or expressed from plasmids.

This study identifies key factors and regulators controlling natural transformation in Lactococcus lactis, revealing a unique regulatory network involving carbon/nitrogen sensors and the Clp degradation machinery.