Abd-El-Monsif Shawky

The paper identifies DDX3X as a dual switch regulator of mRNA translation, promoting or suppressing translation in non-stressed cells and switching roles in acute ER stress.

This study investigates how genetic variants influence gene regulation in cancer by integrating GWAS data with 3D genome structure to identify functional mechanisms of non-coding SNPs.

GraphGR predicts the effect of kinase inhibitors on cancer cell growth using a graph neural network that integrates heterogeneous data, achieving high accuracy on unseen data.