Anastassios Vourekas

An ancestral tRNA maturation enzyme repurposed for cytoplasmic non-coding RNA processing

The paper identifies vtRNAs as direct substrates of ELAC1 and shows ELAC1 has broader RNA substrate specificity compared to ELAC2.

Establishment and functional characterization of bovine endometrial epithelial organoids

This study establishes bovine endometrial epithelial organoids and shows they produce fluid supporting embryo development beyond Day 8 under conventional culture conditions.

Human mascRNA interacts with SUMO E1 and reshapes nuclear SUMOylation

The paper identifies mascRNA as a structured RNA that interacts with SUMO E1 and modulates nuclear SUMOylation, affecting protein homeostasis and nuclear architecture.

DDX3X acts as a selective dual switch regulator of mRNA translation in acute ER stress

The paper identifies DDX3X as a dual switch regulator of mRNA translation, promoting or suppressing translation in non-stressed cells and switching roles in acute ER stress.

All ribosomal RNAs and 45S spacers from humans to worms are packed with organism-specific motifs whose other copies are found predominantly in numerous nervous system genes including many associated with human disorders

The paper identifies primate-specific motifs in human rRNAs and 45S spacers that are also found in nervous system genes linked to disorders like autism and schizophrenia.

Oviduct fluid metabolic regulation of embryonic genome methylation

This study shows that maternal exposure to THC and CBD alters oviduct fluid metabolites, leading to aberrant DNA methylation in embryos without direct exposure to cannabinoids.

The MOV10 RNA helicase is a dosage-dependent host restriction factor for LINE1 retrotransposition in mice

This study shows MOV10 restricts LINE1 retrotransposition in mice in a dosage-dependent manner, affecting reproductive fitness and transcriptome regulation.