Author

Kaice A. LaFavers

Indiana University IndianapolisORCID 0000-0003-2052-6248Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Genomics· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Angela R. SaboiD· 3 shared Tarek M. El‐AchkariD· 3 shared Azuma NanamatsuiD· 2 shared Daria BarwinskaiD· 2 shared Seth WinfreeiD· 2 shared Shehnaz Khan· 2 shared William S. BoweniD· 2 shared Ana C Ricardo· 1 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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3 shared papersCell Biology

Angela R. SaboORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cell BiologybioRxivPreprintOct 12, 2026

Spatial proteomics identifies altered thick ascending limb cells as drivers of kidney disease through uromodulin retention

Azuma Nanamatsu, George J. Rhodes, William S. Bowen…·Tarek M. El‐Achkar

This study identifies altered thick ascending limb cells with UMOD retention as drivers of CKD using spatial proteomics and shows reducing UMOD retention attenuates CKD development.

DOI 10.64898/2026.10.09.756985

humanmouse

𝕏 PostBluesky

PhysiologybioRxivPreprintMar 1, 2026

Uromodulin promotes immune zonation and inhibits alternative inflammasome-mediated activation of immune-to-collecting duct inflammatory signaling in early acute kidney injury

Angela R. Sabo, Azuma Nanamatsu, Dillen Wischmeier…·Kaice A. LaFavers

This study investigates how Uromodulin affects immune zonation and inflammasome activity in kidney injury, showing it reduces inflammation and immune cell interactions in specific kidney regions.

DOI 10.64898/2026.02.26.708299

mousebulk RNA-seq

𝕏 PostBluesky

GenomicsbioRxivPreprintJun 22, 2022

A spatially anchored transcriptomic atlas of the human kidney papilla identifies significant immune injury and matrix remodeling in patients with stone disease

Victor Hugo Canela, William S. Bowen, Ricardo Melo Ferreira…·the Kidney Precision Medicine Project

This study maps the spatial transcriptomic landscape of the human kidney papilla in stone disease, identifying immune injury and matrix remodeling as key features.

1 citation

humanscRNA-seq

𝕏 PostBluesky