Author

Shehnaz Khan

Indiana University Indianapolis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell-cell communication· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Angela R. SaboiD· 2 shared Azuma NanamatsuiD· 2 shared Kaice A. LaFaversiD· 2 shared Tarek M. El‐AchkariD· 2 shared Ana C Ricardo· 1 shared Atsushi KunoiD· 1 shared Azusa Tomioka· 1 shared Connor J. GulbronsoniD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersCell Biology

Angela R. SaboORCID

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2 papers

Recent·Most cited

Spatial proteomics identifies altered thick ascending limb cells as drivers of kidney disease through uromodulin retention

Azuma Nanamatsu, George J. Rhodes, William S. Bowen, Angela R. Sabo, Shehnaz Khan, Mahla Asghari, Dillen L Wischmeier, Daria Barwinska, Takashi Kudo, Azusa Tomioka, Hiroaki Sakaue, Atsushi Kuno, Ana C Ricardo, James Phillip Lash, Katherine R. Tuttle, , Tarek M. El‐Achkar

This study identifies altered thick ascending limb cells with UMOD retention as drivers of CKD using spatial proteomics and shows reducing UMOD retention attenuates CKD development.

bioRxiv · Oct 12, 2026 · PreprintCell Biology

Uromodulin promotes immune zonation and inhibits alternative inflammasome-mediated activation of immune-to-collecting duct inflammatory signaling in early acute kidney injury

Angela R. Sabo, Azuma Nanamatsu, Dillen Wischmeier, Connor J. Gulbronson, Shehnaz Khan, Radmila Micanovic, Seth Winfree, Tarek M. El‐Achkar, Kaice A. LaFavers

This study investigates how Uromodulin affects immune zonation and inflammasome activity in kidney injury, showing it reduces inflammation and immune cell interactions in specific kidney regions.

bioRxiv · Mar 1, 2026 · PreprintPhysiology