Author

Leandro Vieira dos Santos

Serviço Nacional de Aprendizagem IndustrialORCID 0000-0003-2095-4429Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Synthetic Biology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:yeast· 3 Research Focus:gene regulatory network inference· 2 Research Focus:variant calling· 2 Research Focus:benchmarking· 1 Assay:CRISPR screen· 1 Research Focus:genome assembly· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Ana Paula JacobusiD· 2 shared Jeferson GrossiD· 2 shared Joneclei Alves BarretoiD· 2 shared Lucas Souza deiD· 2 shared Danieli Fernanda Canaver MariniD· 1 shared Diego Trindade de SouzaiD· 1 shared Dione Oliveira JordaniD· 1 shared Gabriel Rodrigues Alves MargaridoiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersGenomics

Ana Paula JacobusORCID

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3 papers

Recent·Most cited

GenomicsBiotechnology for Biofuels and BioproductsPeer-reviewedFeb 12, 2026

QTL mapping, breeding, and debugging Saccharomyces cerevisiae strains through Reiterated Mass Selection and backcrosSing (ReMaSSing)

Lucas Souza de, Joneclei Alves Barreto, Diego Trindade de Souza…·Ana Paula Jacobus

This paper introduces ReMaSSing, a method to identify and correct adaptive alleles in Saccharomyces cerevisiae for improved lignocellulosic hydrolysate tolerance through QTL mapping and breeding.

3 citationstop 4%

yeastexperimental assay

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Synthetic BiologyBioresource TechnologyPeer-reviewedSep 17, 2025

Epistatic mutations in ISC metabolism synergize with cell cycle regulation and the PPP to enhance xylose fermentation and acetic acid tolerance in industrial yeast

Leandro Vieira dos Santos, Gisele Cristina de Lima Palermo, Paulo Emílio dos Santos Costa…·Gonçalo Amarante Guimarães Pereira

4 citations

yeastwhole-genome sequencing

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Synthetic BiologyACS Synthetic BiologyPeer-reviewedOct 18, 2022

EasyGuide plasmids support in vivo assembly of gRNAs for CRISPR/Cas9 applications in Saccharomyces cerevisiae

Ana Paula Jacobus, Joneclei Alves Barreto, Lucas Souza de…·Jeferson Gross

The paper introduces EasyGuide plasmids to simplify CRISPR/Cas9 gRNA assembly in yeast by enabling in vivo gRNA generation directly in yeast.

17 citations

yeastCRISPR screen

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