Patricia Renard

This study identifies mitochondrial dysfunction as a key feature of brain senescence in telomerase-deficient mice, linking telomere attrition to impaired mitochondrial function and region-specific neuronal vulnerability.

This study identifies KLF16 as a repressive transcription factor that inhibits HIV-1 transcription by competing with Sp1 and recruiting repressive complexes.

This study identifies and characterizes the Mpc complex in Brucella abortus, showing its essential role in lipid transport between membranes and survival in macrophages.

The paper identifies Gbp2b as an early biomarker of tauopathy in the olfactory epithelium of PS19 mice through transcriptomic analysis across different ages.

The paper investigates the role of the disordered N-terminal region of PcoB in copper homeostasis and stability in Caulobacter vibroides, revealing its importance in Cu efflux and PcoA stabilization.

This study investigates the cooperative role of Emx2 and Dmrta2 in cortex development and reveals distinct functions of Dmrta2 in choroid plexus formation.

This study shows Dmrta2 represses Pax6 in cortical progenitors and identifies a DNA-binding mutation linked to microcephaly in humans.

This study identifies MPV17 as a regulator of mitochondrial calcium and oxidative stress, showing its role in preventing mtDNA degradation through interactions with the MICOS complex.

This study shows that heme synthesis and succinate regulate pluripotent state transitions in ESCs by affecting signaling pathways and triggering 2C-like reprogramming.