Author

Jean‐Philippe Defour

Cliniques Universitaires Saint-LucORCID 0000-0003-3999-5861Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Gabriel LevyiD· 2 shared Anabelle DecottigniesiD· 1 shared Barbara MathieuiD· 1 shared Bénédicte BrichardiD· 1 shared Bernard GalleziD· 1 shared Céline Mouton· 1 shared Christian Pecquet· 1 shared Cyril CorbetiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCell Biology

Gabriel LevyORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintJun 27, 2025

Human mitochondrial DNA variants influence telomere length: evidence from a transmitochondrial cybrid model

Manon Mahieu, Jean‐Philippe Defour, Barbara Mathieu…·Anabelle Decottignies

The paper investigates how mitochondrial DNA variants affect telomere length using transmitochondrial cybrids, finding an inverse correlation between donor telomere length and mitochondrial ROS levels.

DOI 10.1101/2025.06.27.661964

humanexperimental assay

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Molecular BiologyeLifePeer-reviewedJun 20, 2023

Constitutive Activation and Oncogenicity Are Mediated by Loss of Helical Structure at the Cytosolic Boundary of the Thrombopoietin Receptor

Jean‐Philippe Defour, Emilie Leroy, Sharmila Dass…·Stefan N. Constantinescu

The paper investigates how mutations in the thrombopoietin receptor (TpoR) affect its activation and oncogenicity by altering the helical structure at the cytosolic boundary of the transmembrane domain.

10 citations

humanexperimental assay

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