Author

J. D. Karam

University of California, IrvineORCID 0000-0003-2134-9327Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:imaging· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Aileen J. AndersoniD· 3 shared Brian J CummingsiD· 2 shared Pooja S. SakthiveliD· 2 shared Alyssa Villegas· 1 shared Brielle Brown· 1 shared Cynthia Benitez· 1 shared Elizabeth Partida· 1 shared Enrico GrattoniD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersNeuroscience

Aileen J. AndersonORCID

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintJul 3, 2026

Aging reveals domain-specific vulnerability to the chronic behavioral consequences of repetitive mild traumatic brain injury

J. D. Karam, Julian Lopez, Leslie Ortiz…·Brian J Cummings

This study investigates how aging affects the chronic behavioral consequences of repetitive mild traumatic brain injury (rmTBI) in mice, finding age-specific effects on anxiety but not spatial memory.

DOI 10.64898/2026.06.29.735325

mousestatistical model

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NeuroscienceBrain Behavior and ImmunityPeer-reviewedNov 28, 2024

Minimally invasive serial collection of cerebrospinal fluid reveals sex-dependent differences in neuroinflammation in a rat model of mild traumatic brain injury

Josh Karam, Nimrah Ashfaq, Cynthia Benitez…·Brian J Cummings

This study uses minimally invasive CSF collection in a rat mTBI model to show males have a more robust inflammatory response than females.

3 citations

ratproteomics

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NeuroscienceJournal of NeurochemistryPeer-reviewedJul 17, 2024

Organelle phenotyping and multi-dimensional microscopy identify C1q as a novel regulator of microglial function.

Pooja S. Sakthivel, Lorenzo Scipioni, J. D. Karam…·Aileen J. Anderson

The paper introduces an organelle phenotyping approach using live-cell microscopy to identify C1q as a regulator of microglial function, showing its role in fatty acid storage and mitochondrial membrane potential.

3 citations

humanimaging

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