Author

Pooja S. Sakthivel

University of California, IrvineORCID 0000-0002-1422-4609Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Assay:imaging· 2 Research Focus:differential expression· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1 Organism:rat· 1

Frequent Co-Authors

Aileen J. AndersoniD· 3 shared Brian J CummingsiD· 2 shared J. D. KaramiD· 2 shared Alyssa Villegas· 1 shared Andre Obenaus· 1 shared Andrea Anzalone· 1 shared Brielle Brown· 1 shared Courtney M. DumontiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersNeuroscience

Aileen J. AndersonORCID

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Author profile →

3 papers

Recent·Most cited

Microtubule Stabilization and Biomaterial Guidance Synergize to Enhance CST Regeneration and Motor Recovery After Chronic SCI.

Usha Nekanti, Pooja S. Sakthivel, Rebecca A. Nishi, Andrea Anzalone, Courtney M. Dumont, Jeong Bin Lee, Skylar McDonald, Hao Song, Andre Obenaus, Paul David Gershon, Frank Bradke, Lonnie D. Shea, Brian J Cummings, Aileen J. Anderson

This study combines biomaterial scaffolds and microtubule stabilizers to improve axon regeneration and motor recovery in chronic spinal cord injury.

bioRxiv · Feb 8, 2026 · PreprintNeuroscience

Minimally invasive serial collection of cerebrospinal fluid reveals sex-dependent differences in neuroinflammation in a rat model of mild traumatic brain injury

Josh Karam, Nimrah Ashfaq, Cynthia Benitez, Victor Morales, Elizabeth Partida, Michelle Hernandez, Jordan Yokoyama, Alyssa Villegas, Brielle Brown, Pooja S. Sakthivel, Aileen J. Anderson, Brian J Cummings

This study uses minimally invasive CSF collection in a rat mTBI model to show males have a more robust inflammatory response than females.

Brain Behavior and Immunity · Nov 28, 2024Peer-reviewedNeuroscience

Organelle phenotyping and multi-dimensional microscopy identify C1q as a novel regulator of microglial function.

Pooja S. Sakthivel, Lorenzo Scipioni, J. D. Karam, Zahara Keulen, Mathew M. Blurton-Jones, Enrico Gratton, Aileen J. Anderson

The paper introduces an organelle phenotyping approach using live-cell microscopy to identify C1q as a regulator of microglial function, showing its role in fatty acid storage and mitochondrial membrane potential.

Journal of Neurochemistry · Jul 17, 2024Peer-reviewedNeuroscience