Chang Liu

This study identifies PDS5A as a key regulator of chromatin loop extrusion and TAD-like domains in Arabidopsis, revealing a promoter- and motif-based mechanism for loop anchoring and transcriptional control.

The paper presents a lineage-wide evolutionary analysis of 3D genome architecture and organization across brown algae, revealing conserved chromosomal features, lineage-specific rearrangements, and long-term co-evolution of centromeres and retrotransposons.

The paper identifies a sub-functionalized biosynthetic gene cluster in Physalis grisea, showing epigenetic regulation and tissue-specific expression of withanolide biosynthesis.

The paper generates a single-cell chromatin accessibility atlas in nine rat organs, identifies 77 cell types, and analyzes transcription factor dynamics and gene expression conservation across species.

The paper maps the 3D chromatin structure of sex chromosomes in the brown alga Ectocarpus, revealing their spatial organization and links to gene expression and sex determination.

This study shows that PDS5 proteins in Arabidopsis prevent the formation of TAD-like domains in the 3D genome.

The paper shows that the plant nuclear lamina disassembles under stress, altering chromatin organization and transcriptional profiles.

The paper shows that paternal chromosome repression via Polycomb mark H3K27me3 maintains haploid gene dosage in diploid embryos of Marchantia polymorpha.

This paper develops a method to generate chromosome-level, haplotype-resolved genome assemblies using single-cell sequencing of gametes, demonstrating it on apricot trees.

The paper analyzes chromatin organization in the early land plant Marchantia polymorpha, revealing an ancestral role of H3K27me3 in transposon silencing and heterochromatin formation.

The paper presents an improved genome assembly of the European pear using long-read sequencing and other techniques, resulting in a more accurate gene count.