Author

Karin Williams

University of GlasgowORCID 0000-0003-2159-5894Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

A. Philip McMahon· 1 shared Aditi Mandar Atmasidha· 1 shared Alan R. PrescottiD· 1 shared Alessandra Fistrovich· 1 shared Amy Dunne MilleriD· 1 shared Anthony J. ChalmersiD· 1 shared Carly R. CabeliD· 1 shared Christina Duncan· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A. Philip McMahon

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1 paper

Recent·Most cited

Dyr726, a brain-penetrant inhibitor of PI3Kα, Type III receptor tyrosine kinases, and WNT signalling

Vasudha Tandon, Alessandra Fistrovich, Joaquina Nogales, Febe Ferro, Samantha Rokey, Carly R. Cabel, Amy Dunne Miller, Mary Yagel, Christina Duncan, Aditi Mandar Atmasidha, Ira Sharma, Gerrit Wilms, Karin Williams, Richard J. R. Elliott, Timothy Chavez, , Sourav Banerjee

This paper designs and evaluates Dyr726, a brain-penetrant multi-kinase inhibitor that targets PI3Kα, receptor tyrosine kinases, and WNT signaling, showing efficacy in preclinical cancer models.

bioRxiv · Mar 26, 2025 · PreprintCancer Biology