Author

Anthony J. Chalmers

University of GlasgowORCID 0000-0002-1746-7278Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

A. Philip McMahon· 1 shared Aditi Mandar Atmasidha· 1 shared Alan R. PrescottiD· 1 shared Alessandra Fistrovich· 1 shared Amy Dunne MilleriD· 1 shared Andrew PauliD· 1 shared Anke HusmanniD· 1 shared Carly R. CabeliD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

A. Philip McMahon

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintApr 23, 2026

ClonoScreen3D-CRISPRi Uncovers Genetic Modifiers of Radiation Response in Glioblastoma

Sukjun Lee, Anke Husmann, Jianbin Li…·Erica Bello

This study introduces ClonoScreen3D-CRISPRi, a 3D clonogenic survival assay combined with CRISPRi, to identify genetic modifiers of radioresistance in GBM, finding NFKB2, RELB, and CDK9 as potent radiosensitizers.

DOI 10.64898/2026.04.17.719014

humanbulk RNA-seq

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Cancer BiologybioRxivPreprintMar 26, 2025

Dyr726, a brain-penetrant inhibitor of PI3Kα, Type III receptor tyrosine kinases, and WNT signalling

Vasudha Tandon, Alessandra Fistrovich, Joaquina Nogales…·Sourav Banerjee

This paper designs and evaluates Dyr726, a brain-penetrant multi-kinase inhibitor that targets PI3Kα, receptor tyrosine kinases, and WNT signaling, showing efficacy in preclinical cancer models.

DOI 10.1101/2025.03.26.645490

mouseexperimental assay

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