Takhar Kasumov

This paper quantifies histone acetylation turnover and acetyl-CoA sources in vivo using 2H2O labeling and mass spectrometry, showing diet-dependent changes in acetylation dynamics and substrate contributions.

This study integrates multi-omics data from alcohol-fed mice to reveal metabolic and epigenetic changes in early alcohol-associated liver disease, highlighting a shift toward antioxidant responses.

This study investigates metabolic changes in PCCA-deficient hepatocytes, showing reduced fatty acid oxidation and pyruvate carboxylation, leading to impaired gluconeogenesis and lipid synthesis.