Molecular BiologybioRxivPreprint
T606-phosphorylation deprives the function of Kaiso as a transcription and oncogenic factor
Wei Tian, Hongfan Yuan, Sisi Qin…·Dajun Deng
This study shows that AKT1 phosphorylates Kaiso at T606, promoting its cytoplasmic localization and de-repression of CDH1, with reduced phosphorylation linked to gastric cancer progression.
DOI 10.1101/2020.03.23.003509