PhysiologybioRxivPreprint
Mutation of an insulin-sensitive Drosophila insulin-like receptor mutant requires methionine metabolism reprogramming to extend lifespan
Marc Tatar, Wenjing Zheng, Shweta Yadav…·Andrey A. Parkhitko
This paper shows a Drosophila insulin-like receptor mutation extends lifespan by reprogramming methionine metabolism, avoiding insulin resistance and maintaining growth and reproduction.
1 citation