Andrey A. Parkhitko

This study shows that old white adipose tissue can rejuvenate in young hosts through thermogenic remodeling and pathway activation, reversing biological age markers.

This study shows C. elegans uses chromoprotein photosensitization and bacterial metabolic cues to prefer red over blue food, independent of light and photoreceptors.

This paper identifies Cyrene as a geroprotective compound that extends lifespan and healthspan in C. elegans and Drosophila, improving stress resistance and neuroprotection.

This paper shows a Drosophila insulin-like receptor mutation extends lifespan by reprogramming methionine metabolism, avoiding insulin resistance and maintaining growth and reproduction.

This study uses LbNOX in Drosophila to show tissue-specific effects of NADH/NAD+ modulation on aging, revealing that targeting non-neuronal tissues can rejuvenate sleep in aged flies.

The paper shows lysosomal cystine efflux limits TORC1 reactivation during fasting by restricting amino acid availability through TCA cycle intermediates.