James P. Malone

This study shows that daraxonrasib, a pan-RAS(on) inhibitor, effectively inhibits TNBC cell proliferation and tumor growth, either alone or in combination with a MEK inhibitor.

The paper develops a method to detect dynamic changes in enkephalin levels in mice during acute stress, revealing their release and correlation in the nucleus accumbens shell.

This study quantifies kinase protein abundance in human tissues using proteomic mass spectrometry, revealing heterogeneity in breast cancer subtypes and enabling clinical applications.