MicrobiologyProceedings of the National Academy of SciencesPeer-reviewed
Chemical genetic interactions elucidate pathways controlling tuberculosis antibiotic efficacy during infection
Peter O. Oluoch, Eun‐Ik Koh, Megan K. Proulx…·Christopher M. Sassetti
This study identifies in vivo chemical-genetic interactions in tuberculosis that reveal novel drug targets and mechanisms, showing differences from in vitro results and highlighting metabolic dependencies affecting drug efficacy.
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