NeuroscienceCellPeer-reviewed
Immunotherapy-related cognitive impairment after CAR T cell therapy in mice
Anna C. Geraghty, Lehi Acosta-Alvarez, Maria Caterina Rotiroti…·Michelle Monje
This study shows that CAR T cell therapy in mice causes cognitive impairment through CNS immune dysregulation, microglial reactivity, and disrupted oligodendroglial homeostasis.
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