Author

Raymond T. Anderson

West Virginia UniversityORCID 0000-0003-2279-5863Unclaimed ORCID profile · follow to get notified of new preprints

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Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

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David M. SmithiD· 1 shared David Salcedo-TacumaiD· 1 shared Md. Qamrul IslamiD· 1 shared Nadeem AsadiD· 1 shared

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2025-2025 · peak 1/yr

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1 shared paperCell Biology

David M. SmithORCID

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1 paper

Recent·Most cited

Cell BiologyScience AdvancesPeer-reviewedOct 10, 2025

Hyperactive 20S Proteasome Enhances Proteostasis and ERAD in C. elegans via degradation of Intrinsically Disordered Proteins.

David Salcedo-Tacuma, Nadeem Asad, Md. Qamrul Islam…·David M. Smith

This study shows that a hyperactive 20S proteasome in C. elegans improves degradation of misfolded proteins, reduces oxidative damage, and extends lifespan without relying on known proteostasis pathways.

13 citations

C. elegansproteomics

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