Author

Mary Elizabeth Sehl

University of California, Los AngelesORCID 0000-0003-2301-0562Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Assay:DNA methylation· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Patricia A. GanziD· 2 shared Anna Maria StornioloiD· 1 shared Collin Farrell· 1 shared Gannon Cottone· 1 shared Jeanette C. PappiD· 1 shared Jill E. HenryiD· 1 shared Jingyi Jessica LiiD· 1 shared Matteo A. PellegriniiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCancer Biology

Patricia A. GanzORCID

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2 papers

Recent·Most cited

Cancer BiologyBreast Cancer ResearchPeer-reviewedJun 11, 2025

DNA methylation patterns in breast cancer, paired benign tissue from ipsilateral and contralateral breast, and healthy controls.

Saya Dennis, Takahiro Tsukioki, Gannon Cottone…·Susan E. Clare

This study compares DNA methylation profiles of breast tumors, adjacent normal tissues, and healthy controls to identify epigenetic differences and their association with estrogen receptor status.

6 citations

humanDNA methylation

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BioinformaticsbioRxivPreprintOct 31, 2024

Systematic dissection of epigenetic age acceleration in normal breast tissue reveals its link to estrogen signaling and cancer risk

Mary Elizabeth Sehl, Wenbin Guo, Collin Farrell…·Patricia A. Ganz

The paper evaluates epigenetic clocks in normal breast tissue, identifies age acceleration linked to estrogen signaling and cancer risk, and highlights cellular heterogeneity's role in age estimation.

2 citations

humanDNA methylation

𝕏 PostBluesky