Author

Susan E. Clare

Northwestern UniversityORCID 0000-0002-9499-0855Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 4 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:human· 5 Research Focus:differential expression· 4 Approach:experimental assay· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Assay:metabolomics· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Seema Ahsan KhaniD· 5 shared Yuan LuoiD· 3 shared Abul Bashar Mir Md. Khademul IslamiD· 2 shared Curtis W. McCloskeyiD· 2 shared Elizaveta V. BenevolenskayaiD· 2 shared María Paula ZappiaiD· 2 shared Mariana Bustamante EduardoiD· 2 shared Maxim V. FroloviD· 2 shared

Activity by Year

2020-2025 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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5 shared papersCancer Biology

Seema Ahsan KhanORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Reprogramming SREBP1-dependent lipogenesis and inflammation in high-risk breast with licochalcone A: a novel path to cancer prevention

Atieh Hajirahimkhan, Elizabeth T. Bartom, Carolina H. Chung, Xingyu Guo, Kyli Berkley, Seyyedmohsen Hosseinibarkooie, Zahra Assadi, Shao Huan Samuel Weng, Raymond Moellering, Oukseub Lee, Ruohui Chen, Wonhwa Cho, Sriram Chandrasekaran, Susan E. Clare, Seema Ahsan Khan

This study shows licochalcone A suppresses breast cancer growth by targeting SREBP1-dependent lipogenesis and inflammation.

International Journal of Cancer · Nov 27, 2025Peer-reviewedCancer Biology

Medium-Chain Fatty Acid exposure in non-transformed mammary glands leads to pro-tumorigenic alterations associated with aging

Mariana Bustamante Eduardo, Abul Bashar Mir Md. Khademul Islam, Curtis W. McCloskey, María Paula Zappia, Maxim V. Frolov, Rama Khokha, Elizaveta V. Benevolenskaya, Seema Ahsan Khan, Susan E. Clare

This study shows that medium-chain fatty acid exposure in non-transformed mammary glands induces aging-like changes linked to breast cancer risk.

bioRxiv · Oct 1, 2025 · PreprintCancer Biology

DNA methylation patterns in breast cancer, paired benign tissue from ipsilateral and contralateral breast, and healthy controls.

Saya Dennis, Takahiro Tsukioki, Gannon Cottone, Wanding Zhou, Patricia A. Ganz, Mary Elizabeth Sehl, Yuan Luo, Seema Ahsan Khan, Susan E. Clare

This study compares DNA methylation profiles of breast tumors, adjacent normal tissues, and healthy controls to identify epigenetic differences and their association with estrogen receptor status.

Breast Cancer Research · Jun 11, 2025Peer-reviewedCancer Biology

Metabolic shift to serine pathway induced by lipids confers oncogenic properties in non-transformed breast cells

Mariana Bustamante Eduardo, Gannon Cottone, Curtis W. McCloskey, Shiyu Liu, Flávio Romero Palma, María Paula Zappia, Abul Bashar Mir Md. Khademul Islam, Peng Gao, Joel Setya, Saya Dennis, Hongyu Gao, Qian Zhang, Xiaoling Xuei, Yuan Luo, Jason W. Locasale, , Susan E. Clare

The paper shows that lipid metabolism, specifically through OA, shifts metabolic pathways in breast cells, increasing SAM and 2-HG, which contribute to oncogenic properties and epigenetic changes.

Science Advances · Mar 21, 2025Peer-reviewedCancer Biology

Somatic Genetic Aberrations in Benign Breast Disease and the Risk of Subsequent Breast Cancer

Zexian Zeng, Andy H. Vo, Xiaoyu Li, Ali Shidfar, Paulette Saldana, Luis Z. Blanco, Xiaoling Xuei, Yuan Luo, Seema Ahsan Khan, Susan E. Clare

The paper identifies genetic aberrations in benign breast lesions that distinguish breast cancer cases from controls and predict cancer risk.

npj Breast Cancer · Jun 12, 2020Peer-reviewedGenetics