Molecular BiologyNature CommunicationsPeer-reviewed
Cryo-EM Structures of the XPF-ERCC1 Endonuclease Reveal an Auto-Inhibited Conformation and the Basis for Activation
Morgan L. Jones, Fabienne Beuron, Aaron J. Borg…·Neil Q. McDonald
The paper reports cryo-EM structures of XPF-ERCC1 in DNA-free and DNA-bound states, revealing an auto-inhibited conformation and activation mechanism.
50 citations