Author

Peter Virnau

Johannes Gutenberg University MainzORCID 0000-0003-2340-3884Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Approach:mechanistic / dynamical model· 1 Approach:statistical model· 1

Frequent Co-Authors

Adrian Pinto· 2 shared Biswajit PradhaniD· 2 shared Damla Tetiker· 2 shared Eugene KimiD· 2 shared Amar DeepiD· 1 shared Camilla Björkegren· 1 shared Constantinos Chatzicharlampous· 1 shared Erin Cutt· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBiophysics

Adrian Pinto

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintMar 10, 2026

SMC Motor Proteins Operate at the Near-Minimal Forces for DNA Loop Extrusion

Adrian Pinto, Biswajit Pradhan, Damla Tetiker…·Peter Virnau

This study presents a coarse-grained model to simulate SMC motor protein loop extrusion, showing they operate at near-minimal forces to overcome entropic barriers.

DOI 10.64898/2026.03.05.709531

statistical modelchromatin & epigenetic regulation

𝕏 PostBluesky

BiophysicsbioRxivPreprintSep 12, 2024

A DNA tension-dependent tug-of-war between dimeric SMC motors governs loop extrusion directionality

Biswajit Pradhan, Adrian Pinto, Damla Tetiker…·Eugene Kim

This study shows that dimeric SMC motors switch extrusion directionality based on DNA tension, with cohesin being constitutively biased toward one-sided extrusion.

2 citations

mechanistic / dynamical modelchromatin & epigenetic regulation

𝕏 PostBluesky