Author

Adrian Pinto

Johannes Gutenberg University Mainz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Approach:mechanistic / dynamical model· 1 Approach:statistical model· 1

Frequent Co-Authors

Biswajit PradhaniD· 2 shared Damla Tetiker· 2 shared Eugene KimiD· 2 shared Peter VirnauiD· 2 shared Amar DeepiD· 1 shared Camilla Björkegren· 1 shared Constantinos Chatzicharlampous· 1 shared Erin Cutt· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBiophysics

Biswajit PradhanORCID

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2 papers

Recent·Most cited

SMC Motor Proteins Operate at the Near-Minimal Forces for DNA Loop Extrusion

Adrian Pinto, Biswajit Pradhan, Damla Tetiker, Maurice Pierre Schmitt, Eugene Kim, Peter Virnau

This study presents a coarse-grained model to simulate SMC motor protein loop extrusion, showing they operate at near-minimal forces to overcome entropic barriers.

bioRxiv · Mar 10, 2026 · PreprintBiophysics

A DNA tension-dependent tug-of-war between dimeric SMC motors governs loop extrusion directionality

Biswajit Pradhan, Adrian Pinto, Damla Tetiker, Takaharu Kanno, Gemma L. M. Fisher, Martin Dieter Baaske, Erin Cutt, Constantinos Chatzicharlampous, Herwig Schuler, Amar Deep, Kevin D. Corbett, Luís Aragón, Peter Virnau, Camilla Björkegren, Eugene Kim

This study shows that dimeric SMC motors switch extrusion directionality based on DNA tension, with cohesin being constitutively biased toward one-sided extrusion.

bioRxiv · Sep 12, 2024 · PreprintBiophysics