NeuroscienceNucleic Acids ResearchPeer-reviewed
Intra-axonal translation of Khsrp mRNA slows axon regeneration by destabilizing localized mRNAs
Priyanka Patel, Courtney N. Buchanan, Matthew D. Zdradzinski…·Jeffery L. Twiss
This study identifies KHSRP as an axonal RNA-binding protein whose mRNA is locally translated after nerve injury, leading to mRNA destabilization and slowed axon regeneration.
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