Author

Vaibhav Jain

Duke UniversityORCID 0000-0003-2394-3426Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Simon G. GregoryiD· 2 shared Alejandro L. AntoniaiD· 1 shared Alexander M. IshoviD· 1 shared Chloe K. NagasawaiD· 1 shared Daniel T. StarczynowskiiD· 1 shared Dennis C. KoiD· 1 shared Farren B. S. BriggsiD· 1 shared Gaddiel Galarza-MuñoziD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersCancer Biology

Simon G. GregoryORCID

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3 papers

Recent·Most cited

Molecular BiologybioRxivPreprintApr 7, 2026

Non-canonical histone H3.3 and its chaperones HIRA and DAXX participate in the regulation of KSHV latency

Sarah McMahon, Vaibhav Jain, Viacheslav M. Morozov…·Rolf Renne

This study shows that H3.3 and its chaperones HIRA and DAXX regulate KSHV latency by promoting chromatinization and stability of the viral episome.

DOI 10.64898/2026.04.02.716100

experimental assay

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Cancer BiologybioRxivPreprintOct 22, 2024

Inhibition of UBE2N in regulatory T-cells boosts immunity against cancer

Wanying Miao, Vaibhav Jain, Madison Han…·Jennifer Y. Zhang

The paper shows that inhibiting UBE2N in Tregs enhances anti-tumor immunity without causing autoimmunity by converting Tregs into effector-like cells.

3 citations

mousebulk RNA-seq

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Molecular BiologyeLifePeer-reviewedMay 9, 2023

The RNA helicase DDX39B activates FOXP3 RNA splicing to control T regulatory cell fate

Minato Hirano, Gaddiel Galarza-Muñoz, Geraldine Schott…·Mariano A. García-Blanco

This study identifies DDX39B as a regulator of FOXP3 RNA splicing, which influences T regulatory cell fate and immune tolerance, linking it to multiple sclerosis risk.

25 citations

humanbulk RNA-seq

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