Author

Mariano A. García-Blanco

Duke-NUS Medical SchoolORCID 0000-0001-8538-1997Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Shelton S. BradrickiD· 2 shared Steven G. WideniD· 2 shared William Samuel FaggiD· 2 shared Alejandro L. AntoniaiD· 1 shared Benjamin J. BlencoweiD· 1 shared Chloe K. NagasawaiD· 1 shared Debbie R. Kennedy· 1 shared Dennis C. KoiD· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersMolecular Biology

Shelton S. BradrickORCID

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Author profile →

4 papers

Recent·Most cited

The RNA helicase DDX39B activates FOXP3 RNA splicing to control T regulatory cell fate

Minato Hirano, Gaddiel Galarza-Muñoz, Geraldine Schott, Liuyang Wang, Chloe K. Nagasawa, Alejandro L. Antonia, Vaibhav Jain, Xiaoying Yu, Steven G. Widen, Farren B. S. Briggs, Simon G. Gregory, Dennis C. Ko, William Samuel Fagg, Shelton S. Bradrick, Mariano A. García-Blanco

This study identifies DDX39B as a regulator of FOXP3 RNA splicing, which influences T regulatory cell fate and immune tolerance, linking it to multiple sclerosis risk.

eLife · May 9, 2023Peer-reviewedMolecular Biology

Y-box binding protein 1 interacts with dengue virus nucleocapsid and mediates viral assembly

Mayra Diosa Toro, Debbie R. Kennedy, Vanessa Chuo, Vsevolod L. Popov, Julien Pompon, Mariano A. García-Blanco

This study identifies YBX1 as a host factor that interacts with dengue virus nucleocapsid and is required for efficient viral assembly and secretion.

mBio · Feb 22, 2022Peer-reviewedMolecular Biology

Definition of germ layer cell lineage alternative splicing programs reveals a critical role for Quaking in specifying cardiac cell fate

William Samuel Fagg, Naiyou Liu, Ulrich Braunschweig, Karen Larissa Pereira de Castro, Xiaoting Chen, Frederick S. Ditmars, Steven G. Widen, John Paul Donohue, Katalin Módis, William K. Russell, Jeffrey H. Fair, Matthew T. Weirauch, Benjamin J. Blencowe, Mariano A. García-Blanco

The paper identifies alternative splicing programs in three germ layers and shows Quaking's role in cardiac mesoderm specification through splicing regulation.

bioRxiv · Dec 22, 2020 · PreprintMolecular Biology

Ribosomal stalk proteins RPLP1 and RPLP2 promote biogenesis of flaviviral and cellular multi-pass transmembrane proteins

Rafael Kroon Campos, H. R. Sagara Wijeratne, Premal Shah, Mariano A. García-Blanco, Shelton S. Bradrick

This study shows RPLP1 and RPLP2 enhance ribosome elongation and protein stability for flaviviral and cellular multi-pass transmembrane proteins by relieving ribosome pausing.

Nucleic Acids Research · Sep 1, 2020Peer-reviewedMolecular Biology