Kathrin Klee

TOBIAS enables genome-wide analysis of TF binding dynamics using ATAC-seq data, revealing complex TF interactions during zygotic genome activation in humans and mice.

This paper demonstrates that memory-driven computing significantly accelerates NGS data processing and reduces energy consumption for RNA-seq tasks.

The paper develops robust and accurate classifiers for AML diagnosis using blood gene expression data and machine learning across 12,029 samples from 105 studies.

This study investigates how IL4 signalling and NCOR2 regulate the reprogramming of human monocytes into dendritic cells and macrophages, revealing distinct transcriptional and functional profiles based on cytokine exposure timing.