Rui Xia

This study examines the longitudinal relationship between epigenetic aging and cognitive aging in Hispanic/Latino adults, finding that increased age acceleration is linked to lower cognitive function and higher risk of MCI.

The paper identifies two Y-linked mutations in a dioecious plant that regulate a male-female developmental trade-off through a regulatory module involving SUN, KUN, and YUN.

The paper introduces SapBase, a genomic database for Sapindaceae species, integrating genomic data and providing analytical tools for research and comparative studies.

sRNAanno provides a comprehensive database of uniformly-annotated small RNAs in 138 plant species, including miRNAs, phasiRNAs, and hc-siRNAs, along with a visualization tool for NGS sRNA data.

This study identifies 100 loci associated with mitochondrial DNA copy number and finds causal links between mitochondrial function and mortality.

This study identifies 137 genome-wide significant loci associated with DNA methylation biomarkers of ageing using DNAm and SNP data from over 41,000 individuals.

Stand-alone, point-and-click Java toolkit bundling over 100 sequence, BLAST, GO/KEGG enrichment and interactive plotting functions, so wet-lab biologists can analyse sequencing-scale data without the command line.

This study identifies genetic loci specific to periventricular and deep white matter hyperintensities, revealing distinct genetic architectures and potential biological mechanisms.

The paper identifies 161 genome-wide significant genetic associations for cortical structure traits across 34 brain regions, highlighting key biological pathways and gene functions.