Jasmin Wächter

The paper compares single-cell transcriptomes of trophoblast organoids derived from hTSCs and primary CTBs to in vivo trophoblasts, identifying similarities and differences in differentiation trajectories and cell states.

The paper uses single-cell RNA sequencing to map metzincin protease expression in human first trimester trophoblasts and identifies key proteases and their substrates in different differentiation states.

The paper uses scRNA-seq to identify trophoblast states and lineage trajectories in first trimester placentas, finding BCAM as a marker of a primitive progenitor state.