Burak Koksal

Obesogenic diet alters decidual differentiation and cell-cell communication in the mouse uterus

This study uses single-cell RNA sequencing to show how an obesogenic diet affects decidual differentiation and cell-cell communication in the mouse uterus.

Single-cell assessment of trophoblast stem cell-based organoids as human placenta-modeling platforms

The paper compares single-cell transcriptomes of trophoblast organoids derived from hTSCs and primary CTBs to in vivo trophoblasts, identifying similarities and differences in differentiation trajectories and cell states.

Hypoxia induces a transcriptional early primitive streak signature in pluripotent cells enhancing spontaneous elongation and lineage representation in gastruloids

The paper shows hypoxia induces an early primitive streak signature in ES cells, enhancing gastruloid elongation and lineage representation through Hif1-mediated transcriptional changes.