Author

Tijs Vandoorne

VIB-KU Leuven Center for Brain & Disease ResearchORCID 0000-0003-2431-7785Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Organism:Drosophila· 1

Frequent Co-Authors

Jimmy BeckersiD· 2 shared Laura FumagalliiD· 2 shared Ludo Van Den BoschiD· 2 shared Philip Van DammeiD· 2 shared Aaron D. GitleriD· 1 shared Alexander McCampbelliD· 1 shared Ann Swijsen· 1 shared Arpan R. MehtaiD· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersNeuroscience

Jimmy BeckersORCID

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2 papers

Recent·Most cited

NeuroscienceStem Cell ReportsPeer-reviewedApr 22, 2021

Human motor units in microfluidic devices are impaired by FUS mutations and improved by HDAC6 inhibition

Katarina Stoklund Dittlau, Emily N. Krasnow, Laura Fumagalli…·Ludo Van Den Bosch

This study uses a microfluidic model of human motor units to show that FUS mutations impair neurite outgrowth and NMJ formation, which can be mitigated by HDAC6 inhibition.

85 citationstop 2%

humanexperimental assay

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NeuroscienceScience AdvancesPeer-reviewedApr 9, 2021

C9orf72-derived arginine-containing dipeptide repeats associate with axonal transport machinery and impede microtubule-based motility

Laura Fumagalli, Florence L. Young, Steven Boeynaems…·Philip Van Damme

This study shows that C9orf72 repeat expansions produce toxic arginine-rich DPRs that disrupt axonal transport by interacting with microtubules and motor proteins, contributing to ALS/FTD.

95 citationstop 2%

humanDrosophila

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