Author

Ann Swijsen

VIB-KU Leuven Center for Brain & Disease Research

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:Drosophila· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Aaron D. GitleriD· 1 shared Alexander McCampbelliD· 1 shared Arpan R. MehtaiD· 1 shared Bhuvaneish Thangaraj SelvarajiD· 1 shared Catherine M. VerfaillieiD· 1 shared Denitza RaitchevaiD· 1 shared Dietmar Rudolf ThaliD· 1 shared Florence L. YoungiD· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Aaron D. GitlerORCID

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1 paper

Recent·Most cited

C9orf72-derived arginine-containing dipeptide repeats associate with axonal transport machinery and impede microtubule-based motility

Laura Fumagalli, Florence L. Young, Steven Boeynaems, Mathias De Decker, Arpan R. Mehta, Ann Swijsen, Raheem Fazal, Wenting Guo, Matthieu Moisse, Jimmy Beckers, Lieselot Dedeene, Bhuvaneish Thangaraj Selvaraj, Tijs Vandoorne, Vanesa Madan, Marka van Blitterswijk, , Philip Van Damme

This study shows that C9orf72 repeat expansions produce toxic arginine-rich DPRs that disrupt axonal transport by interacting with microtubules and motor proteins, contributing to ALS/FTD.

Science Advances · Apr 9, 2021Peer-reviewedNeuroscience