Author

Haley M. Geertsma

University of OttawaORCID 0000-0003-2434-5057Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Maxime W.C. RousseauxiD· 4 shared Steve M. CallaghaniD· 4 shared Jean-Louis A. ParmasadiD· 3 shared Zoe A. FiskiD· 3 shared Julianna J. TomlinsoniD· 2 shared Konrad M. RickeiD· 2 shared Michael G. SchlossmacheriD· 2 shared Terry R. SukiD· 2 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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4 shared papersNeuroscience

Maxime W.C. RousseauxORCID

Mutual co-authors in cluster

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4 papers

Recent·Most cited

NeuroscienceCell Death and DiseasePeer-reviewedApr 4, 2024

Genetic and pharmacological reduction of CDK14 mitigates synucleinopathy

Jean-Louis A. Parmasad, Konrad M. Ricke, Benjamin Nguyen…·Maxime W.C. Rousseaux

This study shows that reducing CDK14 genetically or pharmacologically decreases alpha-synuclein pathology and improves symptoms in Parkinson's disease models.

10 citations

mousehuman

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Neurosciencenpj Parkinson s DiseasePeer-reviewedMar 19, 2024

A topographical atlas of alpha-Synuclein dosage and cell-type expression in the mouse brain and periphery

Haley M. Geertsma, Zoe A. Fisk, Lillian Sauline…·Maxime W.C. Rousseaux

This study maps the expression and dosage of alpha-Synuclein across cell types in the mouse brain and periphery, identifying high and low expressing cell types and their potential role in Parkinson's disease.

23 citationstop 3%

mousebulk RNA-seq

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NeurosciencebioRxivPreprintSep 9, 2022

Characterizing the differential distribution and targets of Sumo paralogs in the mouse brain

Terry R. Suk, Trina T. Nguyen, Zoe A. Fisk…·Maxime W.C. Rousseaux

The paper characterizes the differential distribution and targets of Sumo paralogs in the mouse brain using knock-in mouse models and proteomic analysis.

1 citation

mouseproteomics

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NeuroscienceHuman Molecular GeneticsPeer-reviewedFeb 18, 2022

Constitutive nuclear accumulation of endogenous alpha-synuclein in mice causes motor dysfunction and cortical atrophy, independent of protein aggregation.

Haley M. Geertsma, Terry R. Suk, Konrad M. Ricke…·Maxime W.C. Rousseaux

38 citationstop 3%

mouseexperimental assay

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