Author

Giorgis Isaac

University of Massachusetts Chan Medical SchoolORCID 0000-0003-2440-2461Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Research Focus:database / resource· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1

Frequent Co-Authors

Abinesh Sarvepalli· 1 shared Aiko BarschiD· 1 shared Alan K. JarmuschiD· 1 shared Alexander A. AksenoviD· 1 shared Alexey A. GurevichiD· 1 shared Andrés Mauricio Caraballo‐RodrígueziD· 1 shared Ansgar KorfiD· 1 shared Anupriya TripathiiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperBioinformatics

Abinesh Sarvepalli

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintOct 14, 2025

HSD17B13 Couples Hepatocyte Lipid Metabolism to Stellate Cell Activation via TGFb-1 Signaling

Naideline Raymond, Lawrence M. Lifshitz, Kyounghee Min…·Michael Czech

This study identifies HSD17B13 as a dual metabolic and profibrotic effector that drives TGFb-1-dependent activation of hepatic stellate cells, linking lipid metabolism to fibrogenesis in MASH.

DOI 10.1101/2025.10.14.682191

humanbulk RNA-seq

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BioinformaticsNature MethodsPeer-reviewedAug 24, 2020

Feature-based Molecular Networking in the GNPS Analysis Environment

Louis-Félix Nothias-Scaglia, Daniel Petras, Robin Schmid…·Pieter C. Dorrestein

The paper introduces FBMN, a method for improving molecular networking by enhancing quantitative analysis and isomer distinction using feature detection and alignment tools in the GNPS platform.

1,660 citationstop 1%

metabolomicsstatistical model

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