Yang Chai

This study identifies PRMT1-SFPQ as a regulator of intron retention in craniofacial development, leading to reduced matrix gene expression through NMD.

This study generates a conditional Irf6 mouse model to investigate its role in periderm and neural crest development, revealing distinct phenotypes in these lineages.

This study investigates the role of Tcf12 in calvarial bone development and motor learning in mice, finding that Tcf12 loss leads to altered bone formation and impaired motor learning.

This study identifies canonical Wnt signaling's role in soft palate development by regulating ciliary homeostasis and mesenchymal cell proliferation.

The paper identifies TGF-β signaling and Creb5 as regulators of Fgf18 in perimysial fibroblasts, which is essential for pharyngeal muscle development in mice.

This study identifies Kdm6b's role in regulating p53 signaling during palatogenesis by enabling Tfdp1 to activate p53 expression through chromatin accessibility.

This study investigates the role of Tcf12 in coronal suture development in mice, showing its embryonic requirement in controlling bone growth and suture boundary formation.