Nicole Simone Treichel

This study identifies a bacterial protease that influences phage susceptibility and links it to host epithelial responses in ulcerative colitis.

This study directly analyzes gut bacterial motility in health and inflammation, finding increased motility in inflamed conditions and diverse swimming behaviors.

This study shows that a plant polyphenol mixture accelerates liver metastasis in mice, suggesting potential immunomodulatory effects that require validation in immunocompetent models.

This study shows that small intestine macrophage dynamics control GBS colonization and invasion in infant mice, with region-specific responses to the pathogen.

This study shows that β7 integrin and L-selectin contribute to DDC-induced cholangiopathy in male mice by promoting immune cell infiltration, gut barrier dysfunction, and microbiota shifts.

The paper establishes a publicly available collection of 340 human gut bacterial strains, including 29 newly described species, and identifies plasmids and megaplasmids within these isolates.

This study shows ICAM-1 protects against adipose tissue inflammation and insulin resistance but worsens liver inflammation and fibrosis in mice with diet-induced obesity.

This study benchmarks shotgun sequencing depth in metagenomics, showing that strain-level analysis and functional insights require deep sequencing, while shallow sequencing has significant limitations.

The paper develops a method to design synthetic microbial communities based on metagenomic data, demonstrating its ability to model disease-associated microbiomes.

This study develops a physiologically-based model of bile acid metabolism in mice to understand its dynamics and implications for disease.