Eva Sticová

This study identifies altered epigenetic regulators and metabolic genes in cholangiocarcinoma, linking them to poor prognosis and metabolic-epigenetic crosstalk.

This study identifies PRMT1 as a critical driver of cholangiocarcinoma growth and immune evasion, showing its inhibition enhances antitumor immunity and synergizes with immunotherapy.

The paper characterizes compartment-specific proteomic changes in liver fibrosis models and identifies potential therapeutic targets.

This study identifies plectin as a critical mediator of mechanical homeostasis in hepatocellular carcinoma, showing that its inhibition suppresses tumor growth and metastasis.

This study shows that plectin is essential for intestinal epithelial integrity and protects against colitis by maintaining mechanical stability and junctional function.