ImmunologybioRxivPreprint
T cells compete via reverse MHC class I signaling at the synapse with dendritic cells to secure Golgi recruitment for activation
Anthi Psoma, Elke M. Muntjewerff, Mara J.T. Nicolasen…·Geert van den Bogaart
The paper shows that DCs use reverse MHC class I signaling to polarize their MTOC and Golgi toward T cells, enabling localized IL-12 release for T cell activation.