Rinse de Boer

The paper shows that alpha-synuclein phase separation can form Lewy body-like structures without pre-existing seeds, suggesting a new mechanism for neurodegeneration.

The paper shows that DCs use reverse MHC class I signaling to polarize their MTOC and Golgi toward T cells, enabling localized IL-12 release for T cell activation.

The paper shows that protein agglomerates in E. coli regulate cytoplasmic rheology, with diffusion inversely correlating with amino acid metabolism protein abundance.

The paper identifies Mar26 as a determinant in cytochrome bc1 complex assembly, showing it connects assembly intermediates to MICOS to coordinate complex III maturation at crista junctions.

This study identifies a congenital disorder of glycosylation caused by a missense variant in the second starting methionine of syntaxin-5, leading to loss of the short isoform and multisystem disease.