Author

Abdulkadir Özkan

Harvard UniversityORCID 0000-0003-2499-7637Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Jeffrey D. MacklisiD· 2 shared A. Nazlı BaşakiD· 1 shared Cameron SadeghiD· 1 shared Eiman AzimiD· 1 shared Hari K. PadmanabhaniD· 1 shared Jessica DiaziD· 1 shared Jessica L. MacDonaldiD· 1 shared Lincoln W. PasquinaiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

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10 top collaborators · 25 mutual co-author links

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2 shared papersNeuroscience

Jeffrey D. MacklisORCID

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2 papers

Recent·Most cited

NeuroscienceeLifePeer-reviewedJan 27, 2026

Directed differentiation of functional corticospinal-like neurons from endogenous SOX6+/NG2+ cortical progenitors

Abdulkadir Özkan, Hari K. Padmanabhan, Seth L. Shipman…·Jeffrey D. Macklis

This study generates corticospinal-like neurons from SOX6+/NG2+ cortical progenitors using a multi-component transcriptional construct, achieving high fidelity in morphology, molecular, transcriptomic, and electrophysiological characteristics.

DOI 10.7554/elife.100340.3

mouseexperimental assay

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NeuroscienceProceedings of the National Academy of SciencesPeer-reviewedNov 2, 2020

An evolutionarily acquired microRNA shapes development of mammalian cortical projections

Jessica Diaz, Verl B. Siththanandan, Victoria Lu…·Suzanne A. Tharin

The paper identifies a microRNA cluster unique to placental mammals that promotes corticospinal neuron identity by repressing LMO4, a callosal gene, thereby contributing to neuronal subtype diversity in the mammalian brain.

32 citations

mousehuman

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